卢坤

发布时间:2015-06-23 08:47:20     作者:    浏览次数: 次

 

卢坤,男,汉族,四川绵竹人。博士,博士后,研究员,硕士研究生导师。美国植物生物学家学会、中国遗传学会、重庆市遗传学会、重庆市生物信息学会会员、重庆市生物化学与分子生物学监事、重庆市高等学校青年骨干教师。

Researchgate主页: https://www.researchgate.net/profile/Kun_Lu3;   Frontiers主页: http://loop.frontiersin.org/people/251444/impact;  ORCiD: https://orcid.org/0000-0003-1370-8633

学习经历

1998-2002:西南农业大学农学与生物科技学院,农学学士

2002-2008:西南大学农学与生物科技学院,农学博士(导师:李加纳教授)

 工作经历

2009-2010:西南大学农学与生物科技学院,生物学博士后(导师:李加纳教授)

2012-2013Department of Horticulture and Landscape Architecture, Purdue University, Postdoctoral fellow (导师:Jian-Kang Zhu教授、美国科学院院士)

2010-2017:西南大学农学与生物科技学院,副研究员,硕士研究生导师

2017-至今:西南大学农学与生物科技学院,研究员,硕士研究生导师

研究方向

1. 油菜产量和抗性分子遗传机制

2.油菜种子发育及表观遗传调控机制

3. 芸薹属植物比较与功能基因组学

主持科研项目

国家重点研发计划子课题:小麦等作物功能基因组研究与应用——油菜、蔬菜重要性状的功能基因组与调控网络,2016年-2020年

国家自然科学基金面上项目:甘蓝型油菜生长素极性运输异常导致茎秆弯曲的分子机制,2016年-2019年

国家高技术研究发展计划(863计划)子课题:大豆、油菜、花生功能基因组研究与应用,2012-2016年

国家自然科学基金青年基金项目:甘蓝型油菜组织特异型启动子的分离与鉴定,2012-2014

教育部博士点新教师基金:甘蓝型油菜BnPAP12基因家族根际有机磷利用的分子机制,2011-2013

重庆市自然科学基金:甘蓝型油菜BnSKIPa基因家族的耐旱分子机理研究,2012-2014

重庆市高等学校青年骨干教师资助计划:甘蓝型油菜组织特异型启动子的分离与鉴定,2012-2013

中国博士后科学基金:芸薹属禹氏三角物种中受磷饥饿诱导的PAP12基因家族的功能进化研究,2009-2010

西南大学博士基金:甘蓝型油菜BnSKIPa基因家族的耐旱分子机理研究,2010-2013年

贵州省烟草科学研究所合作项目:贵州省不同风格特色烟叶形成的分子机制研究2011-2013

西南大学基本科研业务费团队项目:基于代谢谱和比较基因组学的芸薹属木质素代谢途径基因的功能进化研究,2012-2014

西南大学基本科研业务费一般项目:甘蓝型油菜BnPAP12基因参与磷高效利用的分子机理研究,2011-2012

5年发表论文

  1. Lu K*,, Li T, He J, Chang W, Zhang R, Liu M, Yu M, Fan Y, Sun W, Ma J, Qu C, Liu L, Li N, Liang Y, Wang R, Tang Z, Qian W, Xu X, Lei B, Zhang K*, Li J* (2017) qPrimerDB: A thermodynamics-based gene-specific qPCR primer database for 147 organisms. Nucleic Acids Research. doi: 10.1093/nar/gkx725. [Epub ahead of print] IF2016= 10.162.
  2. Zhang K, Wu Z, Tang D, Luo K, Lu H, Liu Y, Dong J, Wang X, Lv C*, Wang J*, Lu K*  (2017) Comparative transcriptome analysis reveals critical function of sucrose metabolism related-enzymes in starch accumulation in the storage root of sweet potato. Frontiers in Plant Science. 8:914. IF2016= 4.30.

  3. Wang J, Xian X, Xu X, Qu C, Lu K, Li J, Liu L*. (2017) Genome-wide association mapping of seed coat color in Brassica napus. Journal of Agricultural and Food Chemistry. doi: 10.1021/acs.jafc.7b01226. [Epub ahead of print]  IF2016= 3.154.
  4. Wei L, Jian H, Lu K, Yin N, Wang J, Duan X, Li W, Liu L, Xu X, Wang R, Paterson AH, Li J (2017) Genetic and transcriptomic analyses of lignin- and lodging-related traits in Brassica napus. Theor Appl Genet. doi: 10.1007/s00122-017-2937-x. [Epub ahead of print]  IF2016= 4.13.

  5. Ma JQ, Jian HJ, Yang B, Lu K, Zhang AX, Liu P, Li JN* (2017) Genome-wide analysis and expression profiling of the GRF gene family in oilseed rape (Brassica napus L.). Gene. 620:36-45. IF2016= 2.41.

  6. Lu K†*, Peng L†, Zhang C, Lu J, Yang B, Xiao Z, Liang Y, Xu X, Qu C, Zhang K, Liu L, Zhu Q, Fu M, Yuan X, Li J* (Corresponding Author) (2017) Genome-wide association and transcriptome analyses reveal candidate genes underlying yield-determining traits in Brassica napus. Frontiers in Plant Science 8: 206. IF2015= 4.49.

  7. Qu C, Jia L, Fu F, Zhao H, Lu K, Wei L, Xu X, Liang Y, Li S, Wang R*, Li J(2017) Genome-wide association mapping and Identification of candidate genes for fatty acid composition in Brassica napus L. using SNP markers. BMC Genomics. 18(1): 232

  8. Lu K, Xiao Z, Jian H, Peng L, Qu C, Fu M, He B, Tie L, Liang Y, Xu X, Li J* (2016) A combination of genome-wide association and transcriptome analysis reveals candidate genes controlling harvest index-related traits in Brassica napus. Scientific Reports 6: 36452. IF2015=5.23.

  9. Qu C, Zhao H, Fu F, Zhang K, Yuan J, Liu L, Wang R, Xu X, Lu K*, Li J-N* (Corresponding Author) (2016) Molecular Mapping and QTL for Expression Profiles of Flavonoid Genes in Brassica napus. Frontiers in Plant Science 7:1691. IF2015= 4.49

  10. Qu C, Zhao H, Fu F, Wang Z, Zhang K, Zhou Y, Wang R, Xu X, Tang Z, Lu K*, Li J-N* (Corresponding Author) (2016) Genome-Wide Survey of Flavonoid Biosynthesis Genes and Gene Expression Analysis between Black and Yellow-Seeded Brassica napus. Frontiers in Plant Science. 7:1755. IF2015= 4.49

  11. Jian H, Lu K, Yang B, Wang T, Zhang L, Zhang A, Wang J, Liu L, Qu C, Li J* (2016) Genome-wide analysis and expression profiling of the SUC and SWEET gene families of sucrose transporters in oilseed rape (Brassica napus L.). Frontiers in Plant Science 7: 1464. IF2015= 4.49

  12. Wei L, Jian H, Lu K, Filardo F, Yin N, Liu L, Qu C, Li W, Du H, Li J* (2016) Genomewide association analysis and differential expression analysis of resistance to Sclerotinia stem rot in Brassica napus. Plant Biotechnology Journal 14(6): 1368-80. IF2014= 6.09

  13. Lu K*, Guo W, Lu J, Yu H, Qu C, Tang Z, Li J, Chai Y, Liang Y* (2015) Genome-wide survey and expression profile analysis of the mitogen-activated protein kinase (MAPK) gene family in Brassica rapa. PLoS ONE 10(7): e0132051. IF2013= 3.534

  14. Qu, C, Fu F, Liu M, Zhao H., Liu C, Li J, Tang Z, Xu X, Qiu X, Wang R.*, Lu K*. (*Corresponding Author) (2015) Comparative transcriptome analysis of recessive male sterility (RGMS) in sterile and fertile Brassica napus Lines. PLoS ONE, 10, e0144118. IF2013= 3.534

  15. Zhu Q, Sui S, Lei X, Yang Z, Lu K, Liu G, Liu YG, Li M*. Ectopic expression of the coleus R2R3 MYB-type proanthocyanidin regulator gene SsMYB3 alters the flower color in transgenic tobacco. PLoS ONE 2015 10(10):e0139392. IF2013= 3.534

  16. Fu Y, Lu K, Qian L, Mei J, Wei D, Peng X, Xu X, Li J, Frauen M, Dreyer F, Snowdon RJ, Qian W*. (2015) Development of genic cleavage markers in association with seed glucosinolate content in canola. Theoretical and Applied Genetics 128(6): 1029-1037. IF2013=3.658

  17. Wang J, Jian H, Wei L, Qu C, Xu X, Lu K, Qian W, Li J, Li M, Liu L* (2015) Genome-wide analysis of seed acid detergent lignin (ADL) and hull content in rapeseed (Brassica napus L.). PLoS ONE 10: e0145045, IF2013= 3.534

  18. Qu C-M, Li S-M, Duan X-J, Fan J-H, Jia L-D, Zhao H-Y, Lu K, Li J-N, Xu X-F, Wang R* (2015) Identification of candidate genes for seed glucosinolate content using association mapping in Brassica napus L. Genes 6:1215-1229. IF2014= 1.15

  19. Du H, Liang Z, Zhao S, Nan MG, Phan Tran LS, Lu K, Huang YB*, Li JN*. (2015) The evolutionary history of R2R3-MYB proteins across 50 eukaryotes: new insights into subfamily classification and expansion. Scientific Reports 5: 11037. IF2013= 5.078

  20. Qu C, Hasan M, Lu K, Liu L, Zhang K, Fu F, Wang M, Liu S, Bu H, Wang R, Xu X, Chen L, Li J* (2015) Identification of QTL for seed coat colour and oil content in Brassica napus by association mapping using SSR markers. Canadian Journal of Plant Science 95: 387-395. IF2013= 0.921

  21. Lei B, Lu K†,*, Ding F, Zhang K, Chen Y, Zhao H, Zhang L, Ren Z, Qu C, Guo W, Wang J, Pan W* (*Corresponding Author) (2014) RNA sequencing analysis reveals transcriptomic variations in tobacco (Nicotiana tabacum) leaves affected by climate, soil, and tillage factors. International Journal of Molecular Sciences 15(4): 6137-6160. IF2013=2.464

  22. Weng CM, Lu JX, Wan HF, Wang SW, Wang Z, Lu K, Liang Y*. (2014) Over-expression of BnMAPK1 in Brassica napus enhances tolerance to drought stress. Journal of Integrative Agriculture 13: 2407-2415.

  23. Lei M, La H, Lu K, Wang P, Miki D, Ren Z, Duan CG, Wang X, Tang K, Zeng L, Yang L, Zhang H, Nie W, Liu P, Zhou J, Liu R, Zhong Y, Liu D, Zhu JK*. (2013) Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns. PNAS 111(1): 527-32. IF2013=9.737

  24. Shengyi Liu, Yumei Liu, Xinhua Yang, Chaobo Tong, David Edwards, Isobel Parkin, Meixia Zhao, Jingyin Yu, Shunmou Huang, Xiyin Wang, Junyi Wang, Kun Lu, Zhiyuan Fang, Ian Bancroft, Tae-Jin Yang, Qiong Hu, Xinfa Wang, Zhen Yue, Haojie Li, Linfeng Yang, Jianxin Ma, Jian Wu, Qing Zhou, Wanxing Wang, Graham King, J. Chris Pires, Changxin Lu, Zhangyan Wu, Sampath Perumal, Zhuo Wang, Hui Guo, Shengkai Pan, Limei Yang, Jiumeng Min, Dong Zhang, Dianchuan Jin, Wanshun Li, Harry Belcram, Jinxing Tu, Mei Guan, Cunkou Qi, Dezhi Du, Jiana Li, Liangcai Jiang, Jacqueline Batley, Andrew Sharpe, Beom-Seok Park, Ruperao Pradeep, Feng Cheng, Nomar Waminal, Ying Huang, Caihua Dong, Li Wang, Jingping Li, Zhiyong Hu, Mu Zhuang, Yi Huang, Junyan Huang, Jiaqin Shi, Desheng Mei, Jing Liu, Tae-Ho Lee, Jinpeng Wang, Huizhe Jin, Zaiyun Li, Xun Li, Jiefu Zhang, Xiao Lu, Yongming Zhou, Zhongsong Liu, Xuequn Liu, Rui Qin, Xu Tan, Wenbin Liu, Yupeng Wang, Yangyong Zhang, Jonghoon Lee, Hyun Hee Kim, France Denoeud, Xun Xu, Xinming Liang, Wei Hua, Xiaowu Wang, Jun Wang, Boulos Chalhoub, Andrew Paterson The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes. Nature Communications. 5: 3930. IF2013=10.015

  25. Lei B, Zhao XH, Zhang K, Zhang J, Ren W, Ren R, Ren Z, Chen Y, Zhao HN, Pan WJ, Chen W, Li HX, Ding FZ*, Lu K*. (Corresponding Author) (2013) Comparative transcriptome analysis of tobacco (Nicotiana tabacum) leaves to identify aroma compound-related genes expressed in different cultivated regions. Molecular Biology Reports 40: 345-357. IF2013=2.506

  26. Qu C, Fu F, Lu K, Zhang K, Wang R, Xu X, Wang M, Lu J, Wan H, Tang Z, Li J*. (2013) Differential accumulation of phenolic compounds and expression of related genes in black- and yellow-seeded Brassica napus. Journal of Experimental Botany 64(10): 2885-2898. IF2013=5.242

  27. Zhang K, Lu K, Qu C, Liang Y, Wang R, Chai Y, Li J*. (2013) Gene silencing of BnTT10 family genes causes retarded pigmentation and lignin reduction in the seed coat of Brassica napus. PLoS ONE 8(4): e61247. IF2013= 3.534

  28. Mei J, Ding Y, Lu K, Wei DY, Liu Y, Disi JO, Li JN, Liu LZ, Liu SY, McKay J, Qian W*. (2013) Identification of genomic regions involved in resistance against Sclerotinia sclerotiorum from wild Brassica oleracea. Theoretical and Applied Genetics 126(2): 549-556. IF2013=3.658

  29. Huang S, Deng L, Guan M, Li J, Lu K, Wang H, Fu D, Mason AS, Liu S, Hua W*. (2013) Identification of genome-wide single nucleotide polymorphisms in allopolyploid crop Brassica napus. BMC Genomics 2013, 14: 717. IF2013=4.397

  30. Wang X, Duan, CG, Tang K, Wang B, Zhang H, Lei M, Lu K, Mangrauthia SK, Wang P, Zhu G, Zhao Y, Zhu JK*. (2013) An RNA-binding protein regulates plant DNA methylation by controlling mRNA processing at intronic heterochromatin-containing genes. PNAS 110(38): 15467–15472. IF2013=9.737

  31. Wei LJ, Xiao ML, Mason AS, Ma B, Lu K, Li JN, Katrin L, Fu DH* (2013) Characterization and evolutionary analysis of Brassica species-diverged sequences containing simple repeat units. Genes & Genomics 35(2): 167-175. IF2013=0.497

  32. Lu K, Qu CM, Zhang K, Lu JX, Chai YR*, Li JN* (2011) Expression quantitative trait loci analysis of BAN, F3H and TT19 genes in Brassica napus, Proceedings of 13th International Rapeseed Congress, ed SPZO s.r.o. (Prague, Czech Republic), 949–952

  33. Lu K, Chai YR, Zhang K, Wang R, Chen L, Lei B, Lu J, Xu XF, Li JN* (2008). Cloning and characterization of phosphorus starvation inducible Brassica napus PURPLE ACID PHOSPHATASE 12 gene family, and imprinting of a recently evolved MITE-minisatellite twin structure. Theoretical and Applied Genetics 117: 963–975. IF2013=3.658

  34. Lu K, Li JN, Zhong WR, Zhang K, Fu FY, Chai YR* (2008) Isolation, characterization and phosphate-starvation inducible expression of potential Brassica napus PURPLE ACID PHOSPHATASE 17 (BnPAP17) gene family. Botanical Studies 49: 199–213. IF2013=0.864

  35. 卢坤,申鸽子,梁颖,符明联,贺斌,铁琳梅,张烨,彭柳,李加纳* (2017) 适合不同产量的环境下油菜高收获指数的产量构成因素分析. 作物学报 43(1): 82-96

  36. 张蕊,邓文亚,杨柳,王亚萍,肖芳枝,禾健,卢坤* (2017) 盐胁迫下甘蓝型油菜发芽期下胚轴和根长的全基因组关联分析. 中国农业科学 50(1): 15−27

  37. 卢坤,王腾岳,徐新福,唐章林,曲存民,贺斌,梁颖,李加纳* (2016) 甘蓝型油菜结角高度与荚层厚度的全基因组关联分析. 作物学报 42(3): 42(3): 344-352

  38. 卢坤,曲存民,李莎,赵会彦,王瑞,徐新福,梁颖,李加纳* (2015) 甘蓝型油菜BnTT3基因的表达与eQTL定位分析. 作物学报41(11): 1758-1766

  39. 卢坤*,张琳,曲存民,梁颖,唐章林,李加纳* (2015) 利用RNA-Seq鉴定甘蓝型油菜叶片干旱胁迫应答基因. 中国农业科学 48(4):630−645

  40. 曲存民卢坤,刘水燕,卜海东,付福友,王瑞,徐新福,李加纳* (2014)黄黑籽甘蓝型油菜类黄酮途径基因SNP位点检测分析. 作物学报 40(11): 1914-1924

  41. 陆俊杏, 卢坤, 朱斌, 彭茜, 陆奇丰, 曲存民, 殷家明, 李加纳, 梁颖*, 柴友荣* (2013) 芸薹属物种(B. napus, B. oleracea, B. rapaMAPK1家族的克隆、进化和表达特征. 国农业科学 46(16):3478−3487

  42. 陆俊杏, 陆奇丰, 张凯, 柴友荣, 李加纳, 钱伟, 吕俊, 卢坤*, 梁颖* (2013) 甘蓝型油菜MAPK1在损伤和病原菌胁迫下的表达模式分析. 中国农业科学 2013, 46(20):4388-4396

  43. 朱斌, 陆俊杏, 彭茜, 翁昌梅, 王淑文, 余浩, 李加纳, 卢坤*, 梁颖* (2013) 甘蓝型油菜MAPK7基因家族及其启动子的克隆与表达分析. 作物学报 39(5): 789−805

  44. 曲存民, 付福友, 卢坤, 谢景梅, 刘晓兰, 黄杰恒, 李波, 王瑞, 谌利, 唐章林, 李加纳* (2011) 不同环境中甘蓝型油菜种皮木质素含量的QTL定位. 作物学报 37, 1398−1405

  45. 卢坤, 张凯, 柴友荣, 陆俊杏, 唐章林, 李加纳* (2010) 甘蓝和白菜紫色酸性磷酸酶17基因家族的克隆和比较分析. 作物学报 36, 517−525

  46. 陆俊杏, 卢坤*, 张凯, 曹廷, 李加纳, 梁颖* (2010) 甘蓝型油菜SAMDC3基因及其启动子的克隆与分析. 基因组学与应用生物学报 29(2), 215-224 

国际学术会议报告

Lu K. Differential accumulation of phenolic compounds and expression of related genes between the black- and yellow-seeded Brassica napus, Initialization Meeting of Crop Germplasm Resources Utilization and Innovation Base (CGRUIB) Programme, July 17-19, 2012, Chongqing, P. R. China

Lu K. Expression quantitative trait loci analysis of BAN, F3H and TT19 genes in Brassica napus, 13th International Rapeseed Congress, June 5–9, 2011, Prague, Czech Republic

Lu K. Expression quantitative trait loci analysis of BAN, F3H and TT19 genes in Brassica napus, 17th Crucifer Genetics Workshop, Sept 5-8, 2010, Saskatoon, Canada

Lu K. Cloning and comparative analysis of phosphate-starvation Brassica PAP12 and PAP17 gene families, Korea-China Joint Workshop on Brassica Genomics, Dec 8, 2009, Suwon, Republic of Korea

Lu K. Genome-wide association analysis of Sclerotinia sclerotiorum and lodging resistance in Brassica napus,14th International Rapeseed Congress, July 5-9, 2015, Saskatoon, Canada

其他学术经历

1. 2009年国际微管植物生物学大会会议(PVBA2009)秘书

2. 2012-至今 中国博士后科学基金评审专家

3. 2013-至今 美国植物生物学家学会会员、中国遗传学会会员、重庆市遗传学会会员

4. 2013-至今 专业学术期刊《Journal of Experimental Botany》、《Journal of Integrative Plant Biology》、《BMC Plant Biology》、《Journal of Agricultural and Food Chemistry》《PLoS ONE》、Plant Biology》、Plant Physiology and Biochemistry》、《Tropical Plant Biology》、《Molecular Biology Reports》、《农业生物技术学报》、《基因组学与应用生物学》和《中国油料作物学报》等杂志审稿专家

5. 2014年 现代农业中功能基因组和遗传学应用国际学术会议(AFGGMA2014)秘书

6. 2015年-至今 国家自然科学基金评审专家

7. 2016年-至今 《Frontiers in Plant Science》杂志编委

研究生招生专业

1. 硕士研究生:植物分子生物学;植物分子遗传;植物功能与比较基因组学

联系方式

电话:023-68250701;传真:023-68250701E-maildrlukun at swu dot edu dot cn

通信地址:重庆市北碚区天生路216号西南大学农学与生物科技学院;邮编:400716